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Download the clinical summary of a recently published review1 summarising why biofilm is a key challenge for clinicians caring for chronic wounds.

  • Biofilm is present in the majority of chronic wounds2
  • It is a key cause of delayed wound healing3 and a precursor to infection4
  • Formation tends to occur when wound moisture and exudate are not well controlled5

Biofilm has an increased tolerance to antimicrobials and antibiotics6

More research is needed to identify a rapid accurate technique to identify and characterise biofilms in ways that optimise their validity in diagnosing or screening patient risk of infection or delayed healing and to inform clinical decisions.1

  1. Hurlow J, Couch K, Laforet K, Bolton L, Metcalf D, Bowler P, 2014.  Clinical Biofilms:  A Challenging Frontier in Wound Care.  Advances in Wound Care, DOI:  10.1089/wound.2014.0567.
  2. James G, Swogger E, Wolcott R, Pulcini E, Secor P, 2008.  Biofilms in chronic wounds.  Wound Repair and Regeneration; 16:37-44.
  3. Metcalf D and Bowler P, 2013.  Biofilm delays wound healing: a review of the evidence. Burns & Trauma; 1:5-12
  4. Percival S and Bowler P, 2004.   Biofilms and their potential role in wound healing.  WOUNDS; 16: 234-240.
  5. Hurlow J and Bowler P, 2012. Potential implications of biofilm in chronic wounds:  a case series.  J Wound Care; 21:109-119.
  6. Burmølle M, Thomsen TR, Fazli M, et al. Biofilms in chronic infections—a matter of opportunity—monospecies biofilms in multispecies infections. FEMS Immunol Med Microbiol 2010;59:324–336.

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